When we spiral down into the deeper layers of anxiety – whether relationship anxiety or any other form that anxiety takes – we find some universal root causes that live at the center. These exist on both the emotional and psychological/spiritual planes, and they all need our attention if we’re going to heal. It requires tremendous courage and fortitude to peer directly into the root causes without the filters of projections or defenses protecting us, as when we peel away the hardened shell that has protected our hearts our entire lives, we come face-to-face with our own soft and defenseless vulnerability.
TFSAggregator installs with sample policy files, as well as an empty main policy file. See https:///using/writing-rules/writing-rules/ and other pages in the User's Guide for more direction. Above is a condensed version of the main policy file that I use (comments removed). I found that not all C# primitives would work on my TFS2013 system, even some scripts shown in the documentation and samples would fail when testing. Thus, I recommend that you code and test in a step-wise fashion.
Like a set of bookends, cellular, molecular, and genetic changes of the beginnings of life mirror those of one of the most common cause of death--metastatic cancer. Epithelial to mesenchymal transition (EMT) is an important change in cell phenotype which allows the escape of epithelial cells from the structural constraints imposed by tissue architecture, and was first recognized by Elizabeth Hay in the early to mid 1980's to be a central process in early embryonic morphogenesis. Reversals of these changes, termed mesenchymal to epithelial transitions (METs), also occur and are important in tissue construction in normal development. Over the last decade, evidence has mounted for EMT as the means through which solid tissue epithelial cancers invade and metastasize. However, demonstrating this potentially rapid and transient process in vivo has proven difficult and data connecting the relevance of this process to tumor progression is still somewhat limited and controversial. Evidence for an important role of MET in the development of clinically overt metastases is starting to accumulate, and model systems have been developed. This review details recent advances in the knowledge of EMT as it occurs in breast development and carcinoma and prostate cancer progression, and highlights the role that MET plays in cancer metastasis. Finally, perspectives from a clinical and translational viewpoint are discussed.